Scientific Publications

Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia

Science Translational Medicine, Berrien-Elliot et al, February 2022

Memory-like differentiation enhances NK cell responses to melanoma

Clin Cancer Res, Marin et al, June 2021

Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations with Response after Adoptive Immunotherapy for Leukemia

Cancer Discovery, Berrien-Elliott et al, December 2020

CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas

Blood, Gang et al, November 2020 

Memory-like natural killer cells for cancer immunotherapy

Seminars in Hematology, Gang et al, November 2020 

Chimeric antigen receptor T cells (CAR-T) for the treatment of T-cell malignancies

Best Practice & Research Clinical Haematology, Cooper and DiPersio, December 2019

An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies

Leukemia, Cooper et al, February 2018

Cytokine-Induced Memory-Like Differentiation Enhances Unlicensed Natural Killer Cell Antileukemia and FcγRIIIa-Triggered Responses

Biol Blood Marrow Transplant, Wagner et al, March 2017 

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia.

Science Translational Medicine, Romee et al, September 2016

Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells.

Biol Blood Marrow Transplant, Leong et al, April 2014

Cytokine activation induces human memory-like NK cells.

Blood, Romee et al, December 2012

Latest News

Wugen to Present Data on WU-NK-101 at the American Association for Cancer Research (AACR) Annual Meeting 2023

— Data demonstrate the potential of WU-NK-101 to reverse primary and acquired mechanisms of immune …

Wugen Announces CEO Transition

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Wugen Presents Data on WU-NK-101 in Combination with Cetuximab in Preclinical Models of Advanced Colorectal Cancer (CRC) at ASCO Gastrointestinal Cancers Symposium

— WU-NK-101 overcomes limitations encountered with other adoptive cell therapies in solid tumors — –WU-NK-101 …

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