Wugen Technology

WU-NK

Memory Natural Killer (NK) Cells Have Enhanced Anti-Tumor Function

WU-CART

Fratricide-resistant off-the-shelf CAR-T

Healthy T-cells and malignant T-cells share the same surface proteins (target antigens)

Deletion of the target antigen from the surface of the engineered CAR T-cell, that is derived from a healthy donor T-cell, prevents self-killing (fratricide) while ensuring CAR T-cells kill malignant T-cells

Deletion of the T-cell receptor (TCR) enables the use of T-cells from healthy donors without the risk of life-threatening Graft vs. Host Disease (GvHD)

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